Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

…, N Schweinfurth, C Kettelhack, JPK Doll… - Translational …, 2022 - nature.com
A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions affected …

Fecal microbiota transplantation (FMT) as an adjunctive therapy for depression—case report

JPK Doll, JF Vázquez-Castellanos, AC Schaub… - Frontiers in …, 2022 - frontiersin.org
Depression is a debilitating disorder, and at least one third of patients do not respond to
therapy. Associations between gut microbiota and depression have been observed in recent …

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a …

E Schneider, JPK Doll, N Schweinfurth… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: In major depressive disorder (MDD), cognitive dysfunctions strongly contribute
to functional impairments but are barely addressed in current therapies. Novel treatment …

[HTML][HTML] Effects of a probiotic add-on treatment on fronto-limbic brain structure, function, and perfusion in depression: Secondary neuroimaging findings of a …

…, N Schweinfurth, C Kettelhack, JPK Doll… - Journal of Affective …, 2023 - Elsevier
Background Probiotics are suggested to improve depressive symptoms via the microbiota-gut-brain
axis. We have recently shown a beneficial clinical effect of probiotic supplementation …

[HTML][HTML] Neural mapping of anhedonia across psychiatric diagnoses: A transdiagnostic neuroimaging analysis

…, L Mählmann, C Kettelhack, EE Engeli, JPK Doll… - NeuroImage: Clinical, 2021 - Elsevier
Anhedonia has been associated with abnormal reward-related striatal dopamine functioning
in patients with different psychiatric disorders. Here, we tested whether anhedonia …

[HTML][HTML] Effectiveness of a Mindfulness-Based Mobile Application for the Treatment of Depression in Ambulatory Care: Protocol for a Randomized Controlled Trial

J Sarlon, JPK Doll, A Schmassmann… - JMIR Research …, 2022 - researchprotocols.org
Background Patients with major depressive disorder (MDD) often experience relapses
despite regular treatment with pharmacotherapy and psychotherapy. Further, long waiting lists …

[HTML][HTML] Wake up and get some sleep: Reviewing workplace napping and charting future directions

A Anand, R Tóth, JL Doll, SK Singh - European Management Journal, 2024 - Elsevier
Although research demonstrates the importance of napping for health and well-being within
work settings, the topic has resulted in limited empirical investigations, fragmented literary …

Examining immune-inflammatory mechanisms of probiotic supplementation in depression: secondary findings from a randomized clinical trial

L Sempach, J Doll, V Limbach, F Marzetta, AC Schaub… - 2024 - researchsquare.com
We recently indicated that four-week probiotic supplementation significantly reduced
depression along with microbial and neural changes in people with depression. Here we further …

Outpatient end of life discussions shorten hospital admissions in gynecologic oncology patients

KM Doll, JE Stine, L Van Le, DT Moore, V Bae-Jump… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: The study goal was to determine whether prior outpatient exposure to hospice
discussion altered the inpatient course and end-of-life (EOL) care among patients ultimately …

Fatness-associated FTO gene variant increases mortality independent of fatness–in cohorts of Danish men

…, T Hansen, O Pedersen, TIA Sørensen, T Jess - PLoS …, 2009 - journals.plos.org
Background The A-allele of the single nucleotide polymorphism (SNP), rs9939609, in the
FTO gene is associated with increased fatness. We hypothesized that the SNP is associated …