User profiles for Nimmy Varghese

Nimmy Varghese

PhD Student University of Basel
Verified email at unibas.ch
Cited by 914

[HTML][HTML] Dietary mitophagy enhancer: a strategy for healthy brain aging?

N Varghese, S Werner, A Grimm, A Eckert - Antioxidants, 2020 - mdpi.com
Recently, nutritional interventions have received attention as promising approaches to
promote human health during a lifespan. The Mediterranean and Okinawan diets have been …

[HTML][HTML] Higher hair cortisol concentrations associated with shorter leukocyte telomere length in high-risk young adults

D Bürgin, N Varghese, A Eckert, V Clemens… - Scientific Reports, 2022 - nature.com
Chronic stress is associated with accelerated biological aging as indexed by short age-adjusted
leukocyte telomere length (LTL). Exploring links of biological stress responses with LTL …

[HTML][HTML] Distinct acute effects of LSD, MDMA, and d-amphetamine in healthy subjects

…, F Müller, L Ley, R Duerig, N Varghese… - …, 2020 - nature.com
Lysergic acid diethylamide (LSD) is a classic psychedelic, 3,4-methylenedioxymethamphetamine
(MDMA) is an empathogen, and d-amphetamine is a classic stimulant. All three …

[HTML][HTML] Adverse and traumatic exposures, posttraumatic stress disorder, telomere length, and hair cortisol–Exploring associations in a high-risk sample of young adult …

D Bürgin, V Clemens, N Varghese, A Eckert… - Brain, Behavior, & …, 2022 - Elsevier
Background Childhood adversities (CAs), potentially traumatic exposures (PTEs), and
posttraumatic stress disorder (PTSD) are known to increase the risk for poor health outcomes, …

[HTML][HTML] Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects

…, P Dolder, M Stocker, U Duthaler, N Varghese… - …, 2021 - nature.com
Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric
research and therapy. However, no modern studies have evaluated subjective and autonomic …

[HTML][HTML] Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects

…, U Duthaler, KE Kolaczynska, N Varghese… - …, 2022 - nature.com
Growing interest has been seen in using lysergic acid diethylamide (LSD) and psilocybin in
psychiatric research and therapy. However, no modern studies have evaluated differences …

Acute effects of psilocybin after escitalopram or placebo pretreatment in a randomized, double‐blind, placebo‐controlled, crossover study in healthy subjects

…, U Duthaler, N Varghese… - Clinical …, 2022 - Wiley Online Library
The psychedelic psilocybin is being investigated for the treatment of depression and anxiety.
Unclear is whether antidepressant treatments interact with psilocybin. The present study …

[HTML][HTML] Acute effects of intravenous DMT in a randomized placebo-controlled study in healthy participants

…, U Duthaler, D Rudin, D Luethi, N Varghese… - Translational …, 2023 - nature.com
N,N-dimethyltryptamine (DMT) is distinct among classic serotonergic psychedelics because
of its short-lasting effects when administered intravenously. Despite growing interest in the …

[HTML][HTML] Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in …

…, U Duthaler, D Luethi, N Varghese… - …, 2023 - nature.com
Mescaline, lysergic acid diethylamide (LSD), and psilocybin are classic serotonergic psychedelics.
A valid, direct comparison of the effects of these substances is lacking. The main goal …

Low doses of LSD acutely increase BDNF blood plasma levels in healthy volunteers

…, F Holze, ME Liechti, N Varghese… - ACS pharmacology & …, 2020 - ACS Publications
Despite preclinical evidence for psychedelic-induced neuroplasticity, confirmation in humans
is grossly lacking. Given the increased interest in using low doses of psychedelics for …