Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a …

E Schneider, JPK Doll, N Schweinfurth… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: In major depressive disorder (MDD), cognitive dysfunctions strongly contribute
to functional impairments but are barely addressed in current therapies. Novel treatment …

Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

AC Schaub, E Schneider… - Translational …, 2022 - nature.com
A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions …

The effects of probiotics on symptoms of depression: Protocol for a double-blind randomized placebo-controlled trial

CJK Wallace, JA Foster, CN Soares, RV Milev - Neuropsychobiology, 2020 - karger.com
Background: A growing body of evidence has linked mental health outcomes to the gut
microbiome. This has led to the investigation of the GI tract as a target for novel treatments …

Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial

A Kazemi, AA Noorbala, K Azam, MH Eskandari… - Clinical Nutrition, 2019 - Elsevier
Background Disturbance in the equilibrium of the gut microbiota has been involved in the
pathophysiology of depression. Probiotics have the potential to healthfully modulate the gut …

[HTML][HTML] The efficacy, safety, and tolerability of probiotics on depression: clinical results from an open-label pilot study

CJK Wallace, RV Milev - Frontiers in psychiatry, 2021 - frontiersin.org
Background: A growing body of research has shown that consumption of probiotics can
improve symptoms associated with mood and anxiety disorders through activity of the gut …

[HTML][HTML] Mechanisms of cognitive impairment in depression. May probiotics help?

M Dobielska, NK Bartosik, KA Zyzik… - Frontiers in …, 2022 - frontiersin.org
Depression is the major cause of disability globally. Apart from lowered mood and
accompanying symptoms, it leads to cognitive impairment that altogether predicts …

Probiotics for the treatment of depressive symptoms: an anti-inflammatory mechanism?

C Park, E Brietzke, JD Rosenblat, N Musial… - Brain, Behavior, and …, 2018 - Elsevier
During the past decade, there has been renewed interest in the relationship between brain-
based disorders, the gut microbiota, and the possible beneficial effects of probiotics …

[HTML][HTML] Effects of a probiotic add-on treatment on fronto-limbic brain structure, function, and perfusion in depression: Secondary neuroimaging findings of a …

G Yamanbaeva, AC Schaub, E Schneider… - Journal of Affective …, 2023 - Elsevier
Background Probiotics are suggested to improve depressive symptoms via the microbiota-
gut-brain axis. We have recently shown a beneficial clinical effect of probiotic …

Multispecies probiotic administration reduces emotional salience and improves mood in subjects with moderate depression: a randomised, double-blind, placebo …

R Baião, LP Capitão, C Higgins, M Browning… - Psychological …, 2023 - cambridge.org
Background The potential antidepressant properties of probiotics have been suggested, but
their influence on the emotional processes that may underlie this effect is unclear. Methods …

[HTML][HTML] A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood

L Steenbergen, R Sellaro, S van Hemert… - Brain, behavior, and …, 2015 - Elsevier
Background: Recent insights into the role of the human microbiota in cognitive and affective
functioning have led to the hypothesis that probiotic supplementation may act as an adjuvant …