Article Figures & Tables
Figures
- Fig. 1
Percent signal change and regional activation illustrating a treatment-emotion processing interaction (error bars represent standard error of the mean). AMY = amygdala; IFG = inferior frontal gyrus; ROI = region of interest.
Tables
- Table 1
Peak amygdala and IFG activation of the interaction between treatment and affective experience
Peak voxel (MNI) Group contrast; region k Peak t value* p value‡ x y z Interaction effect Right IFG 283 7.91† < 0.001 38 52 0 4.75† 0.010 40 40 4 4.21† 0.016 38 44 −12 4.15† 0.017 42 44 −10 Left amygdala 50 5.18† 0.006 −20 2 −16 4.79† 0.009 −20 −4 −18 Positive pictures Escitalopram > placebo Left amygdala 56 2.24 0.013 −20 0 −16 1.95 0.025 −22 −4 −22 Placebo > escitalopram Right IFG 48 2.39 0.009 48 42 0 Left IFG 29 2.05 0.021 −44 40 −4 Negative pictures Escitalopram > placebo Right IFG 349 3.05 0.001 40 54 2 2.49 0.007 48 54 2 2.43 0.008 44 42 2 2.35 0.010 48 46 10 Left IFG 115 2.60 0.005 −44 48 8 2.31 0.011 −40 44 −4 Placebo > escitalopram Left amygdala 104 4.42 0.006§ −26 −2 −12 4.33 0.007§ −26 2 −16 Right amygdala 109 3.13 0.001 24 2 −12 3.07 0.001 24 4 −16 Neutral pictures Escitalopram > placebo Left IFG 105 2.90 0.002 −38 30 −2 Left IFG 70 2.45 0.008 −36 10 12 2.14 0.017 −42 8 6 Placebo > escitalopram Right IFG 56 2.63 0.005 58 24 30 2.17 0.015 56 16 28 2.00 0.023 50 20 24 1.87 0.031 48 24 24 Right IFG 30 1.96 0.025 48 40 14 1.96 0.026 48 38 18 1.86 0.032 40 40 8 1.81 0.035 44 44 8 1.89 0.030 42 46 −6 1.89 0.030 42 44 −12 1.89 0.030 38 50 0 1.84 0.033 42 50 −2
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Impact of acute administration of escitalopram on the processing of emotional and neutral images: a randomized crossover fMRI study of healthy women
