Article Figures & Tables
Figures
- Fig. 1
Whole brain difference of functional connectivity strength maps among 3 groups. The colour bar indicates the statistical significance threshold. The left side of the image corresponds to the left hemispheric regions. Map thresholds were set at p < 0.05 with multiple comparisons. HC = healthy controls; L = left; OCD = obsessive–compulsive disorder; R = right; REL = first-degree relatives of patients with OCD.
- Fig. 2
The overlapping regions of abnormal functional connectivity strength in patients with obsessive–compulsive disorder (OCD) and their healthy first-degree relatives. The box plot represents connectivity strength values of the 3 groups at the peak of the overlapping regions. Blue denotes the healthy control group, green denotes the first-degree relative group or abnormal brain regions in first-degree relatives, red denotes patients with OCD or abnormal brain regions in these patients, and yellow denotes the overlapping regions of abnormal functional connectivity strength regions between patients with OCD and their healthy first-degree relatives. *p < 0.001; #p > 0.05. MTG = middle temporal gyrus; OFC = orbitofrontal cortex.
- Fig. 3
Abnormal interregional correlations in the patients with obsessive–compulsive disorder (OCD) and their first-degree relatives. Red denotes the brain regions with increased functional connectivity (FC) and blue denotes the brain regions with reduced functional connectivity. Map thresholds were set at p < 0.05 with multiple comparisons. ACC = anterior cingulate cortex; HC = healthy controls; IFG = inferior frontal cortex; L = left; MTG = middle temporal gyrus; OFC = orbitofrontal cortex; PCC = posterior cingulate cortex; PreCG = precentral gyrus; R = right; REL = first-degree relatives of patients with OCD; ROI = region of interest.
Tables
Group; mean ± SD* Characteristics OCD, n = 39 Relatives, n = 20 Control, n = 39 F2,95 p value Sex, male:female 20:19 10:10 20:19 0.096 0.95 Age, yr 26.6 ± 9.8 29.5 ± 8.6 26.0 ± 6.3 1.352 0.27 Education, yr 12.6 ± 3.3 12.9 ± 2.9 13.1 ± 3.2 0.078 0.93 Disease duration, mo 45.3 ± 37.3 — — — — HAM-D total score 6.5 ± 5.9 — — — — HAM-A total score 10.2 ± 3.6 — — — — Y-BOCS total score 26.7 ± 6.1 — — — — HAM-A = Hamilton Rating Scale for Anxiety; HAM-D = Hamilton Rating Scale for Depression; OCD = obsessive–compulsive disorder; SD = standard deviation; Y-BOCS = Yale–Brown Obsessive Compulsive Scale.
↵* Unless otherwise indicated.
In this issue
Article tools
