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Research Paper

Reduced activation in the ventral striatum during probabilistic decision-making in patients in an at-risk mental state

Franziska Rausch, Daniela Mier, Sarah Eifler, Sabrina Fenske, Frederike Schirmbeck, Susanne Englisch, Claudia Schilling, Andreas Meyer-Lindenberg, Peter Kirsch and Mathias Zink
J Psychiatry Neurosci May 01, 2015 40 (3) 163-173; DOI: https://doi.org/10.1503/jpn.140191
Franziska Rausch
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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  • For correspondence: [email protected]
Daniela Mier
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Sarah Eifler
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Sabrina Fenske
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Frederike Schirmbeck
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Susanne Englisch
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Claudia Schilling
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Andreas Meyer-Lindenberg
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Peter Kirsch
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Mathias Zink
From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
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Article Information

vol. 40 no. 3 163-173
DOI 
https://doi.org/10.1503/jpn.140191
PubMed 
25622039
History 
  • Received July 10, 2014
  • Revision received September 12, 2014
  • Revision received October 10, 2014
  • Accepted October 15, 2014
  • Published online May 1, 2015.
Copyright & Usage 
© 2015 8872147 Canada Inc.

Author Information

  1. Franziska Rausch, PhD⇑,
  2. Daniela Mier, PhD,
  3. Sarah Eifler, MSc,
  4. Sabrina Fenske, MSc,
  5. Frederike Schirmbeck, PhD,
  6. Susanne Englisch, PhD,
  7. Claudia Schilling, PhD,
  8. Andreas Meyer-Lindenberg, PhD,
  9. Peter Kirsch, PhD,
  10. Mathias Zink, PhD
  1. From the Department of Psychiatry and Psychotherapy (Rausch, Eifler, Englisch, Schilling, Meyer-Lindenberg, Zink) and the Department of Clinical Psychology (Mier, Fenske, Kirsch), Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; and the Academic Medical Centre, Amsterdam University, Netherlands (Schirmbeck).
  1. Correspondence to: F. Rausch, Central Institute of Mental Health, Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim/Heidelberg University J5D-68159, Mannheim, Germany; franziska.rausch{at}zi-mannheim.de
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Journal of Psychiatry and Neuroscience: 40 (3)
J Psychiatry Neurosci
Vol. 40, Issue 3
1 May 2015
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Reduced activation in the ventral striatum during probabilistic decision-making in patients in an at-risk mental state
Franziska Rausch, Daniela Mier, Sarah Eifler, Sabrina Fenske, Frederike Schirmbeck, Susanne Englisch, Claudia Schilling, Andreas Meyer-Lindenberg, Peter Kirsch, Mathias Zink
J Psychiatry Neurosci May 2015, 40 (3) 163-173; DOI: 10.1503/jpn.140191

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Reduced activation in the ventral striatum during probabilistic decision-making in patients in an at-risk mental state
Franziska Rausch, Daniela Mier, Sarah Eifler, Sabrina Fenske, Frederike Schirmbeck, Susanne Englisch, Claudia Schilling, Andreas Meyer-Lindenberg, Peter Kirsch, Mathias Zink
J Psychiatry Neurosci May 2015, 40 (3) 163-173; DOI: 10.1503/jpn.140191
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