Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)

From the Department of Basic and Clinical Neuroscience, King’s College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray)