Research Paper
Altered response to risky decisions and reward in patients with obsessive–compulsive disorder
Pedro Silva Moreira, Julian Macoveanu, Paulo Marques, Ana Coelho, Ricardo Magalhães, Hartwig R. Siebner, José Miguel Soares, Nuno Sousa and Pedro Morgado
J Psychiatry Neurosci March 01, 2020 45 (2) 98-107; DOI: https://doi.org/10.1503/jpn.180226
Pedro Silva Moreira
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MSc, PhDJulian Macoveanu
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MSc, PhDPaulo Marques
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MEng, PhDAna Coelho
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MEngRicardo Magalhães
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MEng, PhDHartwig R. Siebner
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MD, DMScJosé Miguel Soares
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MEng, PhDNuno Sousa
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
MD, PhDPedro Morgado
From the Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the ICVS/3Bs, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Clinical Academic Centre, Braga, 4710-057 Braga, Portugal (Moreira, Marques, Coelho, Magalhães, Soares, Sousa, Morgado); the Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (Macoveanu); the Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark (Macoveanu, Siebner); the Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København, Denmark (Siebner); and the Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark (Siebner)
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Altered response to risky decisions and reward in patients with obsessive–compulsive disorder
Pedro Silva Moreira, Julian Macoveanu, Paulo Marques, Ana Coelho, Ricardo Magalhães, Hartwig R. Siebner, José Miguel Soares, Nuno Sousa, Pedro Morgado
J Psychiatry Neurosci Mar 2020, 45 (2) 98-107; DOI: 10.1503/jpn.180226
Altered response to risky decisions and reward in patients with obsessive–compulsive disorder
Pedro Silva Moreira, Julian Macoveanu, Paulo Marques, Ana Coelho, Ricardo Magalhães, Hartwig R. Siebner, José Miguel Soares, Nuno Sousa, Pedro Morgado
J Psychiatry Neurosci Mar 2020, 45 (2) 98-107; DOI: 10.1503/jpn.180226
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