Peptidergic neurons of the Edinger–Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in humans who died by suicide

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)

From the Department of Pharmacology and Pharmacotherapy, Medical School and Molecular Pharmacology Research Group, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Kormos, Kecskés, Alomari, Hegedüs, Helyes, Pintér); the Department of Anatomy, Medical School and Research Group for Mood Disorders, Centre for Neuroscience, Szentágothai Research Centre, University of Pécs, Pécs, Hungary (Farkas, T. Gaszner, Csernus, Hegedüs, B. Gaszner); Human Brain Tissue Bank and Laboratory, Semmelweis University, Budapest, Hungary (Renner, Palkovits); the Department of Physiology, Medical School, Szentágothai Research Centre, Centre for Neuroscience, University of Pécs, Pécs, Hungary (Zelena); Pharm-InVivo Ltd., Pécs, Hungary (Helyes, Pintér)