Research Paper
Open Access
Multimetric structural covariance in first-episode major depressive disorder: a graph theoretical analysis
Chujun Chen, Zhening Liu, Chang Xi, Wenjian Tan, Zebin Fan, Yixin Cheng, Jun Yang, Lena Palaniyappan and Jie Yang
J Psychiatry Neurosci May 04, 2022 47 (3) E176-E185; DOI: https://doi.org/10.1503/jpn.210204
Chujun Chen
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Zhening Liu
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Chang Xi
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Wenjian Tan
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Zebin Fan
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Yixin Cheng
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Jun Yang
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Lena Palaniyappan
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)
Jie Yang
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the National Clinical Research Centre for Mental Disorders, Changsha, China (Chen, Liu, Xi, Tan, Fan, Cheng, Jun Yang, Jie Yang); the Department of Psychiatry, University of Western Ontario, London, Ont. (Palaniyappan); the Robarts Research Institute, University of Western Ontario, London, Ont. (Palaniyappan); the Lawson Health Research Institute, London, Ont. (Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Quebec (Palaniyappan)

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Multimetric structural covariance in first-episode major depressive disorder: a graph theoretical analysis
Chujun Chen, Zhening Liu, Chang Xi, Wenjian Tan, Zebin Fan, Yixin Cheng, Jun Yang, Lena Palaniyappan, Jie Yang
J Psychiatry Neurosci May 2022, 47 (3) E176-E185; DOI: 10.1503/jpn.210204