RT Journal Article SR Electronic T1 Ziprasidone therapy for post-traumatic stress disorder JF Journal of Psychiatry and Neuroscience JO JPN FD Canadian Medical Association SP 430 OP 431 VO 30 IS 6 A1 Zakaria Siddiqui A1 William A. Marcil A1 Subhash C. Bhatia A1 Sriram Ramaswamy A1 Frederick Petty YR 2005 UL http://jpn.ca/content/30/6/430.abstract AB We describe the cases of 2 men with chronic combat-induced post-traumatic stress disorder (PTSD) who benefited from therapy with ziprasidone. They did not have active psychotic symptoms. Both the patients had a history of inadequate response to previous trials of different psychotropic agents. Ziprasidone was considered because of its broad-spectrum actions on various neurotransmitters. To our knowledge, this is the first published report of the usefulness of ziprasidone in the pharmacotherapy of PTSD, although atypical antipsychotic agents (e.g., olanzapine, quetiapine and risperidone) have been reported to be beneficial in the treatment of this condition.