PT  - JOURNAL ARTICLE
AU  - Jeanne Talbot
AU  - Jennifer L. Phillips
AU  - Pierre Blier
TI  - Ketamine for chronic depression: two cautionary tales
AID  - 10.1503/jpn.190073
DP  - 2019 Nov 01
TA  - Journal of Psychiatry and Neuroscience
PG  - 384--385
VI  - 44
IP  - 6
4099  - http://jpn.ca/content/44/6/384.short
4100  - http://jpn.ca/content/44/6/384.full
SO  - J Psychiatry Neurosci2019 Nov 01; 44
AB  - A growing body of literature has shown the effectiveness of ketamine for treating chronic depression. How long the beneficial effects of repeated ketamine last once infusions are stopped, however, remains largely unknown. Understanding the challenges that ensue after ketamine cessation can help clinicians optimally guide patients who opt for ketamine treatment and minimize the associated risks. In this commentary, we discuss some unexpected data gathered from participants of a pilot study on the effects of adjunctive ketamine infusion for resistant depression.