RT Journal Article
SR Electronic
T1 The need for speed: an update on methamphetamine addiction
JF Journal of Psychiatry and Neuroscience
JO JPN
FD Canadian Medical Association
SP 301
OP 313
VO 31
IS 5
A1 Alasdair M. Barr
A1 William J. Panenka
A1 G. William MacEwan
A1 Allen E. Thornton
A1 Donna J. Lang
A1 William G. Honer
A1 Tania Lecomte
YR 2006
UL http://jpn.ca/content/31/5/301.abstract
AB The psychostimulant methamphetamine (MA) is a highly addictive drug that has surged in popularity over the last decade in North America. A burgeoning number of clandestine drug laboratories has led to dramatic increases in MA production, which have resulted in significant public health, legal and environmental problems. Current evidence indicates that exposure to MA is neurotoxic, and neuroimaging studies confirm that long-term use in humans may lead to extensive neural damage. These physiological changes are commonly associated with persistent forms of cognitive impairment, including deficits in attention, memory and executive function. In the present review, we provide a comprehensive description of the factors relating to MA use and the major health-related consequences, with an emphasis on MA-induced psychosis. It is hoped that increased knowledge of MA abuse will provide the basis for future treatment strategies.