Table 5

Summary of p values for relationships between Childhood Trauma Questionnaire scores and volumetric measurements in participants with MDD (n = 33)

ScoreAmygdalaHippocampusSubfields within hippocampal subregions
TotalSubregionsSubfieldsHeadBodyTail
Total score*Right amygdala: rs: −0.324, p < 0.033
Right basolateral complex: rs: −0.311, p < 0.040
Right accessory basal nucleus: rs: −0.361, p < 0.020
Right basal nucleus: rs: −0.288, p < 0.05		Left hippocampus: rs: −0.347, p < 0.024; p < 0.048†
Right hippocampus: rs: −0.283, p < 0.06		Left head: rs: −0.518, p < 0.001; p < 0.002†
Right head: rs: −0.369, p < 0.018; p < 0.018†		Left cornu ammonis: rs: −0.560, p < 0.001; p < 0.002†
Right cornu ammonis: rs: −0.395, p < 0.012		Left cornu ammonis: rs: −0.633, p < 0.001; p < 0.001†
Right cornu ammonis: rs: −0.412, p < 0.009; p < 0.043†
Right dentate gyrus: rs: −0.299, p < 0.046
Left subiculum: rs: −0.319, p < 0.036		——
Emotional abuse*Right amygdala: rs: −0.359, p < 0.021
Right basolateral complex: rs: −0.343, p < 0.026
Right accessory basal nucleus: rs: −0.448, p < 0.005
Right basal nucleus: rs: −0.375, p < 0.016
Left basal nucleus: rs: −0.293, p < 0.049
Right cortical group: rs: −0.383, p < 0.015		Left hippocampus: rs: −0.246, p < 0.09
Right hippocampus: rs: −0.236, p < 0.09		Left head: rs: −0.419, p < 0.008
Right head: rs: −0.311, p < 0.040		Left cornu ammonis: rs: −0.423, p < 0.007
Right cornu ammonis: rs: −0.381 p < 0.015		Left cornu ammonis: rs: −0.557, p < 0.001; p < 0.012†
Right cornu ammonis: rs: −0.386, p < 0.014
Left subiculum: rs: −0.254, p < 0.08		——
Physical abuse*—Left hippocampus: rs: −0.229, p < 0.1
Right hippocampus: rs: −0.386, p < 0.014		Left head: rs: −0.396, p < 0.012
Right head: rs: −0.453, p < 0.004; p < 0.037†		Left cornu ammonis: rs: −0.393, p < 0.012
Right cornu ammonis: rs: −0.479 p < 0.002		Left cornu ammonis: rs: −0.403, p < 0.011
Right cornu ammonis: rs: −0.476, p < 0.003
Right dentate gyrus: rs: −0.481 p < 0.002
Left subiculum: rs: −0.248, p < 0.08		——
Sexual abuse*—Left hippocampus: rs: −0.288, p < 0.053Left head: rs: −0.245, p < 0.09NSRight dentate gyrus: rs: −0.432, p < 0.006Left dentate gyrus: rs: −0.345, p < 0.025—
Emotional neglect‡—Left hippocampus: rs: −0.367, p < 0.018
Right hippocampus: r: −0.295, p < 0.049		Left head: r: −0.439, p < 0.005; p < 0.043†
Right head: r: −0.280, p < 0.06		Left cornu ammonis: r: −0.539, p < 0.001; p < 0.018†
Right cornu ammonis: r: −0.258, p < 0.07		Left cornu ammonis: r: −0.536, p < 0.001; p < 0.018†
Right cornu ammonis: r: −0.277, p < 0.06
Left subiculum: r: −0.281, p < 0.06		Right dentate gyrus: r: −0.248, p < 0.08—
Physical neglect*——Left head: rs: −0.519, p < 0.001; p < 0.01†
Right head: rs: −0.334, p < 0.029		Left cornu ammonis: rs: −0.536, p < 0.001; p < 0.019†
Right cornu ammonis: rs: −0.330, p < 0.031		Left cornu ammonis: rs: −0.600, p < 0.001; p < 0.004†
Right cornu ammonis: rs: −0.410, p < 0.009
Left subiculum: rs: −0.298, p < 0.046		——

  • MDD = major depressive disorder.

  • ↵* Spearman’s correlation.

  • ↵† Corrected p values for those that survived Holm–Bonferroni correction; p value for total amygdala was not adjusted for multiple comparisons because of our initial hypothesis.

  • ↵‡ Pearson’s correlation.