Demographic and clinical characteristics of the study sample (n = 110)*
| Characteristic | No psychotic symptoms | Psychotic symptoms | p value |
|---|---|---|---|
| Participants, no. | 62 | 48 | — |
| Female sex, no. (%) | 31 (50.0) | 33 (68.8) | 0.08 |
| Mean age ± SD, yr | 13.7 ± 3.4 | 14.5 ± 4.1 | 0.28 |
| Siblings, no. (%) | 11 (17.8) | 12 (25.0) | 0.49 |
| Anxiety disorder, no. (%) | 21 (33.9) | 25 (52.1) | 0.09 |
| Parent diagnosis, no. (%) | 0.12 | ||
| None | 18 (29.0) | 6 (12.5) | — |
| Depression | 23 (37.1) | 27 (56.3) | — |
| Bipolar disorder | 17 (27.4) | 13 (27.1) | — |
| Schizophrenia | 4 (6.5) | 2 (4.2) | — |
| Parent psychosis, no. (%) | 11 (17.8) | 9 (18.8) | 1.00 |
| Cannabis use, no. (%) | 7 (11.3) | 6 (12.5) | 1.00 |
| Stimulant use, no. (%) | 2 (3.2) | 6 (12.5) | 0.08 |
| Mean FSIQ score ± SD | 106.2 ± 14.3 | 107.9 ± 11.3 | 0.51 |
| Mean eTIV ± SD, cm3 | 1522.2 ± 138.6 | 1427.8 ± 168.0 | 0.002 |
eTIV = estimated total intracranial volume; FSIQ = Full Scale Intelligence Quotient; SD = standard deviation.
↵* We compared demographic and clinical variables using t tests for continuous variables and χ2 tests for categorical variables.