Participant characteristics, MAVAN*
| Characteristics | Total (n = 73) | Low ePRS (n = 39) | High ePRS (n = 34) | p value† |
|---|---|---|---|---|
| Male, n (%) | 35 (47.9) | 20 (51.3) | 15 (44.1) | 0.54 |
| Age at scan, yr | 9.27 ± 1.46 | 9.35 ± 1.41 | 9.17 ± 1.53 | 0.60 |
| Gestational age, wk | 39.18 ± 1.18 | 39.03 ± 1.16 | 39.35 ± 1.20 | 0.24 |
| Birth weight, g | 3265 ± 476 | 3223 ± 429 | 3314 ± 527 | 0.42 |
| Breastfeeding duration, mo | 7.37 ± 4.88 | 6.96 ± 4.79 | 7.81 ± 5.01 | 0.46 |
| Smoking during pregnancy, n (%) | 13 (18.1) | 6 (15.8) | 7 (20.6) | 0.60 |
| Maternal education, university degree or above, n (%) | 38 (52.1) | 20 (51.3) | 18 (52.9) | 0.89 |
| Low income, n (%) | 11 (16.9) | 5 (13.9) | 6 (20.7) | 0.47 |
ePRS = expression-based polygenic risk score; MAVAN = Maternal Adversity, Vulnerability and Neurodevelopment.
↵* Data are presented as n (%) or mean ± standard deviation. Percentages were calculated based on the available data; for smoking during pregnancy, total n = 72, and for low income, total n = 65.
↵† We found no significant differences between children in the low and high ePRS groups.