Table 2

Participant characteristics, replication cohort (UCI)*

CharacteristicsTotal (n = 80)Low ePRS (n = 44)High ePRS (n = 36)p value†
Male, n (%)48 (60.0)26 (59.1)22 (61.1)0.86
Corrected age at scan, d21.08 ± 14.7921.39 ± 16.2720.69 ± 12.950.84
Gestational age, wk39.18 ± 1.4939.15 ± 1.6739.22 ± 1.260.83
Birth weight, g3336 ± 5073361 ± 5543305 ± 4500.62
Breastfeeding duration, mo6.41 ± 5.075.37 ± 4.897.7 ± 5.090.07
Smoking during pregnancy, n (%)6 (7.5)3 (6.8)3 (8.3)0.77
Maternal education, university degree or above, n (%)27 (33.8)12 (27.2)15 (41.6)0.13
Household income < $29 999/yr26 (32.5)14 (31.8)12 (33.3)0.28

  • ePRS = expression-based polygenic risk score; UCI = University of California, Irvine.

  • ↵* Data are presented as n (%) or mean ± standard deviation. Percentages were calculated based on the available data.

  • ↵† We found no significant differences between children in the low and high ePRS groups.