Table 2

Changes in Mini-Mental State Examination (MMSE) scores of patients with hypoactive delirium from previous MMSE (T−1) to the time of diagnosis (T0), 1 hour after the first dose (T1) and at a stable dose of methylphenidate (T2)

TimeNo. of patientsMMSE score
MedianMeanStandard deviation
T−1102828.50.9
T01421*20.94.9
T11427†24.94.7
T21328‡27.82.4

  • Note: Significance was calculated using a matched, paired Wilcoxon signed rank test (2-tail distribution).

  • ↵* Comparing T0 with T−1, p = 0.005.

  • ↵† Comparing T1 with T0, p < 0.001.

  • ↵‡ Comparing T2 with T1, p = 0.02.