Table 4

Interaction between CYPs and quetiapine

EnzymeInvolved in metabolism of quetiapineInhibited by quetiapine; in vitro data only
In vitroIn vivo
Case reportsCase series
CYP1A2−−−
CYP2C9−
CYP2C19−−
CYP2D6−−−
CYP3A4+++−