Table 5

Interaction between CYPs and ziprasidone

EnzymeInvolved in metabolism of ziprasidoneInhibited by ziprasidone; in vitro data only
In vitroIn vivo
Case reportsCase series
CYP1A2−
CYP2C9−
CYP2C19−
CYP2D6−+ (NC)
CYP2E1−
CYP3A4+++ (NC)