Table 1

Demographic and clinical characteristics of healthy controls with and without a family history of MDD and patients with MDD

	Group; mean (SD)^*
Characteristic	HC-FHN, n = 64	HC-FHP, n = 30	MDD, n = 33	χ^2/F	p value
Sex, female:male	28:36	13:17	14:19	χ²₂ = 0.16	1.00
Age, yr	30.4 (8.3)	30.7 (8.0)	32.0 (8.0)	F_2,125 = 0.5	0.60
Weight, kg	70.0 (12.5)	73.5 (11.7)	76.0 (20.0)	F₂,₁₂₅ = 1.4	1.40
Height, cm	174.0 (9.7)	176.0 (10.4)	175.0 (8.7)	F_2,125 = 0.7	0.50
Illness duration, yr	—	—	3.4 (5.0)	—	—
21-item Hamilton Rating Scale for Depression (17) score	—	—	23.0 (5.1)	—	—
Age at onset, yr	—	—	28.7 (8.0)	—	—
Alcohol intake, median (mean rank) g/d	5.7 (62.5)	5.6 (71.0)	1.4 (46.0)	χ²_2,125 = 3	0.20^†

HC-FHN = healthy controls without a family history of depression; HC-FHP = healthy controls with a family history of depression; MDD = major depressive disorder; SD = standard deviation.
↵* Unless otherwise indicated.
↵† Kruskal–Wallis test.