Table 1

Effects of valproate on 5-HT–induced intraplatelet Ca mobilization

VPA, μg/mLEffect; mean (and SEM)
Base, nMIncrease, nM
055.3 (1.9)104.8 (5.1)
1055.3 (1.6)98.7 (6.7)
5054.7 (1.5)92.4 (5.9)*
10052.7 (2.1)84.3 (4.8)
100055.9 (1.8)42.7 (5.4)
  • VPA = valproate.

  • n = 13

  • * p < 0.05 compared with group without VPA.

  • p < 0.01 compared with group without VPA.