Summary of results comparing medication, HAM-D scores and platelet serotonin measures at first and second visit
Patient ID | Paroxetine dose, mg/d | HAM-D scores | Platelet serotonin content | |||||
---|---|---|---|---|---|---|---|---|
Flow cytometry, % platelet serotonin | HPLC-ECD, ng serotonin/109 platelets | |||||||
1st | 2nd | 1st | 2nd | 1st | 2nd | 1st | 2nd | |
1 | 0 | 50 | 25 | 18 | 40 | 27 | 468 | 1 |
2 | 0 | 40 | 20 | 3 | 43 | 14 | 833 | 16 |
3 | 0 | 40 | 23 | 2 | 55 | 23 | 623 | 1 |
4 | 0 | 20 | 24 | 3 | 43 | 14 | 504 | 14 |
5 | 0 | 20 | 20 | 1 | 36 | 11 | 623 | 16 |
6 | 10 | 20 | 25 | 1 | 61 | 53 | 755 | 733 |
7 | 10 | 40 | 21 | 2 | 31 | 12 | 515 | 105 |
8 | 10 | 20 | 22 | 3 | 42 | 14 | 67 | 40 |
9 | 20 | 40 | 23 | 7 | 28 | 17 | 1 | 1 |
10 | 20 | 30 | 20 | 8 | 46 | 28 | 24 | 6 |
11 | 30 | 50 | 19 | 3 | 43 | 22 | 10 | 1 |
12 | 10 | 22 | 28 | 186 | ||||
13 | 20 | 21 | 28 | 335 |
HAM-D = Hamilton Depression Rating Scale score; HPLC-ECD = high-pressure liquid chromatography with electrochemical detection.