Comparison of neuropsychological test scores across diagnostic groups after adjusting for covariates
| Test | Diagnostic group; median (and interquartile range) | df | F | p | ||||
|---|---|---|---|---|---|---|---|---|
| MDE-R | MDE-S | Other | Unaffected | |||||
| Sample size | 15 | 6 | 11 | 17 | ||||
| Digits forward | 9 (8–10) | 9 (7–10) | 9 (8–10) | 9 (8–11) | 3 | 27 | 0.567 | 0.641 |
| Digits reverse | 7 (6–9) | 7 (7–8) | 6 (6–8) | 7 (6–9) | 3 | 27 | 0.390 | 0.761 |
| FAS | 36 (34–47) | 34 (28–38) | 36 (30–50) | 40 (29–46) | 3 | 27 | 0.951 | 0.430 |
| RCF | ||||||||
| Copy | 36 (35–36) | 36 (36–36) | 36 (36–36) | 36 (36–36) | 3 | 26 | 0.236 | 0.870 |
| Recall | 23 (21–28) | 26 (20–30) | 27 (20–30) | 23 (18–29) | 3 | 26 | 0.659 | 0.585 |
| Snow | 66 (61–79) | 72 (56–84) | 75 (54–85) | 64 (53–81) | 3 | 26 | 0.641 | 0.595 |
| Stroop | ||||||||
| No. words | 112 (93–112) | 102 (94–111) | 100 (94–110) | 112 (98–112) | 3 | 23 | 1.126 | 0.359 |
| Errors | 5 (4–6) | 2 (1–4) | 2 (0–3) | 2 (1–3) | 3 | 23 | 8.940 | < 0.001 |
| RAVLT | ||||||||
| Immediate memory | 6 (4–8) | 6 (6–6) | 5 (4–7) | 7 (5–8) | 3 | 27 | 0.871 | 0.468 |
| Learning rate | 7 (5–8) | 4 (2–6) | 5 (3–8) | 6 (3–8) | 3 | 27 | 2.116 | 0.122 |
| Total learning | 52 (44–58) | 44 (40–47) | 44 (42–52) | 51 (46–59) | 3 | 27 | 0.073 | 0.974 |
| Delayed recognition | 9 (7–12) | 9 (7–11) | 10 (8–12) | 12 (11–13) | 3 | 27 | 0.953 | 0.429 |
| WCST | ||||||||
| No. categories | 3 (2–4) | 4 (4–5) | 3 (3–4) | 4 (2–5) | 3 | 27 | 0.048 | 0.986 |
| Trials to first categories | 11 (11–16) | 12 (12–19) | 11 (11–12) | 11 (11–12) | 3 | 27 | 0.679 | 0.573 |
| Maintenance of cognitive set | 0 (0–0) | 0 (0–0) | 1 (0–1) | 0 (0–0) | 3 | 27 | 1.241 | 0.314 |
| Perseverative errors | 12 (9–28) | 10 (8–12) | 9 (7–12) | 9 (8–16) | 3 | 27 | 2.624 | 0.071 |
MDE-R = recurrent major depression; MDE-S = single lifetime episode of depression; RAVLT = Rey Auditory Verbal Learning Test; RCF = Rey Complex Figure; Stroop = Stroop Colour Word Test; WCST =Wisconsin Card Sorting Test.