Demographic characteristics of cohort 1 and cohort 2 across either genotype (those with and without s allele) or paroxetine exposure (high v. low exposure at week 2 or 3)
| Characteristic | No. of subjects (and %)* | |||
|---|---|---|---|---|
| No s allele | With s allele | Exposure | ||
| High† | Low‡ | |||
| Cohort 1, n | 19 | 28 | 9 | 36 |
| African American | 2 (10.5) | 4 (14.3) | 1 (11.1) | 5 (13.9) |
| Female:male (% female) | 14:5 (74) | 23:5 (82) | 8:1 (88.9) | 26:10 (72.2) |
| Mean age (and SD), y | 72.0 (7.8) | 70.8 (7.4) | 74.2 (6.9) | 69.0 (7.2) |
| Mean weight (and SD), kg | 71.5 (18.6) | 75.7 (21.4) | 72.0 (20.0) | 72.9 (19.4) |
| Cohort 2, n | 21 | 42 | 23 | 40 |
| African American | 2 (9.5) | 2 (4.8) | 1 (4.3) | 3 (7.5) |
| Female:male (% female) | 11:10 (52) | 29:13 (69) | 20:3 (87) | 20:20 (50) |
| Mean age (and SD), y | 78.1 (5.5) | 76.9 (5.8) | 77.3 (4.8) | 77.1 (5.7) |
| Mean weight (and SD), kg | 73.7 (15.0) | 69.8 (15.3) | 69.9 (14.6) | 72.9 (15.0) |