Table 2

Abnormal functional connectivity in patients with OCD^*

	Group; mean (SD) correlation r
Correlation; brain regions	Control	OCD	t value	p value	Distance
Decreased positive correlation in OCD
Left posttemporal and left anterior fusiform	0.193 (0.166)	0.037 (0.206)	2.306	0.028	51.740
Left posttemporal and left anterior prefrontal cortex	0.293 (0.267)	0.087 (0.294)	2.114	0.042	129.869
Increased positive correlation in OCD
Midcingulate and left postcingulate	0.247 (0.189)	0.469 (0.193)	−3.395	0.002	34.554
Right frontal cortex and right anterior thalamus	0.010 (0.206)	0.193 (0.211)	−2.586	0.014	45.486
Midcingulate and right postcingulate	0.278 (0.219)	0.432 (0.179)	−2.289	0.029	32.016
Right intraparietal sulcus and left precuneus	0.271 (0.163)	0.404 (0.212)	−2.115	0.042	40.571
Midcingulate and left posttemporal	0.135 (0.272)	0.320 (0.238)	−2.096	0.044	63.537
Right inferior cerebellum and left inferior cerebellum	0.337 (0.310)	0.545 (0.204)	−2.079	0.046	37.054

OCD = obsessive–compulsive disorder; SD = standard deviation.
↵* The r values indicate Pearson correlation coefficients of the resting state blood oxygen level–dependent (BOLD) signal between regions in either the patients with OCD or controls. Correlation coefficients in bold indicate significant interregional association of resting state BOLD signal within group (p < 0.05, false discovery rate [FDR]–corrected). The t and p values showed significant differences in correlation between the 2 groups (p < 0.05, uncorrected). Note that pairs of regions were only listed if they met the following criteria: they were significantly nonzero in either the OCD group, control group, or both at p < 0.05 (FDR–corrected), and they showed significant between-group differences at p < 0.05 (uncorrected). The table shows the changes in positive correlations in the OCD group. For changes in negative correlations, see Appendix 2, available online at cma.ca/jpn.