Parameter statistics* | Covariate statistics* | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NTC v. PTSD | NTC v. TC | TC v. PTSD | Age | ICV | Hemisphere | |||||||||
Imaging; brain region | F2,44 | p value | t44 | p value | t44 | p value | t44 | p value | F1,44 | p value | F1,44 | p value | F1,48 | p value |
Parcellation | ||||||||||||||
Bilateral isthmus of the cingulate | 3.98 | 0.025 | −2.59 | 0.013 | −2.48 | 0.017 | −0.04 | 0.97 | 14.66 | < 0.001 | 41.65 | < 0.001 | 1.12 | 0.30 |
Bilateral lateral orbitofrontal cortex | 2.38 | 0.10 | −1.49 | 0.14 | −2.17 | 0.035 | 0.84 | 0.41 | 9.02 | 0.004 | 13.57 | < 0.001 | 123.95 | < 0.001 |
Left rostral middle frontal cortex | 4.12 | 0.022 | −2.68 | 0.010 | −0.84 | 0.40 | −2.03 | 0.048 | 8.33 | 0.006 | 6.82 | 0.012 | — | |
Right inferior parietal cortex | 4.57 | 0.016 | −3.02 | 0.004 | −1.90 | 0.06 | −1.20 | 0.24 | 4.92 | 0.031 | 28.22 | < 0.001 | — | |
VBM grey matter volumes (extracted with MarsBaR) | — | |||||||||||||
Left isthmus of the cingulate | 5.45 | 0.008 | −3.26 | 0.002 | −2.41 | 0.020 | −0.87 | 0.39 | 3.69 | 0.06 | 16.46 | < 0.001 | — | |
Right inferior parietal cortex | 6.69 | 0.003 | −3.65 | < 0.001 | −2.03 | 0.049 | −1.75 | 0.09 | 12.93 | < 0.001 | 9.62 | 0.003 | — | |
Left rostral anterior cingulate cortex | 4.75 | 0.013 | −3.03 | 0.004 | −2.30 | 0.026 | −0.75 | 0.46 | 7.34 | 0.010 | 10.59 | 0.002 | — | |
Right rostral anterior cingulate cortex | 6.01 | 0.005 | −3.24 | 0.002 | −2.96 | 0.005 | −0.22 | 0.83 | 3.29 | 0.08 | 12.20 | 0.001 | — |
ICV = intracranial volume; NTC = nontraumatized control group; PTSD = posttraumatic stress disorder; TC = traumatized control group; VBM = voxel-based morphometry.
↵* All tests were 2-tailed, with p < 0.001 indicating a significant group difference.