Table 1

Demographic, clinical, and SPECT imaging data of healthy female control subjects and female patients with borderline personality disorder

CharacteristicsGroup; mean (and SD)*p value
Control subjectsPatients
No. of subjects98
Age, yr25.9 (3.49)23.2 (5.16)NS
Impulsiveness
BIS total60.11 (7.08)83.75 (9.63)< 0.01
BIS-AI20.0 (3.43)30.63 (4.84)< 0.01
BIS-MI18.0 (1.94)26.38 (2.72)< 0.01
BIS-NI22.11 (3.37)26.75 (3.77)< 0.05
[123-I] ADAM binding
Brainstem0.44 (0.12)0.63 (0.23)< 0.05
Hypothalamus0.99 (0.10)1.05 (0.11)< 0.05
  • SPECT = single photon emission computed tomography; SD = standard deviation; NS = not statistically significant; BIS = Barratt Impulsiveness Scale; AI = attentional impulsivity; MI = motor impulsivity; NI = nonplanning impulsivity.

  • * Unless otherwise indicated.