Characteristics | Group; mean (and SD)* | p value | |
---|---|---|---|
Control subjects | Patients | ||
No. of subjects | 9 | 8 | — |
Age, yr | 25.9 (3.49) | 23.2 (5.16) | NS |
Impulsiveness | |||
BIS total | 60.11 (7.08) | 83.75 (9.63) | < 0.01 |
BIS-AI | 20.0 (3.43) | 30.63 (4.84) | < 0.01 |
BIS-MI | 18.0 (1.94) | 26.38 (2.72) | < 0.01 |
BIS-NI | 22.11 (3.37) | 26.75 (3.77) | < 0.05 |
[123-I] ADAM binding | |||
Brainstem | 0.44 (0.12) | 0.63 (0.23) | < 0.05 |
Hypothalamus | 0.99 (0.10) | 1.05 (0.11) | < 0.05 |
SPECT = single photon emission computed tomography; SD = standard deviation; NS = not statistically significant; BIS = Barratt Impulsiveness Scale; AI = attentional impulsivity; MI = motor impulsivity; NI = nonplanning impulsivity.
↵* Unless otherwise indicated.