Foci of white matter abnormalities in patients at clinical risk for psychosis (p < 0.05, FWE-corrected)
| No.* | MNI coordinate | |||||||
|---|---|---|---|---|---|---|---|---|
| Group comparison; brain region | First group | Second group | Side | x | y | z | No. voxels | Z score |
| Controls > ARMS | 41 | 39 | ||||||
| Superior temporal gyrus | Left | −56 | −38 | 20 | 102 | 3.96 | ||
| Superior frontal gyrus | Left | −18 | 32 | 48 | 29 | 3.34 | ||
| ARMS > controls | 41 | 39 | ||||||
| Insula | Right | 46 | −12 | 18 | 114 | 3.94 | ||
| Angular gyrus | Right | 42 | −62 | 36 | 89 | 3.86 | ||
| ARMS-NT > ARMS-T | 29 | 10 | ||||||
| Precuneus | Left | −16 | −62 | 50 | 257 | 4.29 | ||
| Middle termporal gyrus | Right | 40 | −70 | 26 | 45 | 3.66 | ||
| ARMS-T > ARMS-NT | 10 | 29 | ||||||
| Middle frontal gyrus | Right | 24 | 36 | 38 | 30 | 3.58 | ||
ARMS = at-risk mental state; ARMS-NT = subgroup of patients without transition to psychosis; ARMS-T = subgroup of patients with transition to psychosis; FWE = family-wise error; MNI = Montreal Neurological Institute.
↵* Sample size for the first and second group in the specified comparison.