Functional neuroimaging studies included in the meta-analysis
| Study | Year | Imaging | No. of patients | Treatment | No. of foci |
|---|---|---|---|---|---|
| McGuire et al. (11) | 1994 | H215O PET | 4 | No | 9 |
| Rauch et al. (12) | 1994 | C15O2 PET | 8 | Free for 2 wk | 5 |
| Breiter et al. (13) | 1996 | 1.5-T fMRI | 8 | Yes (n = 8) | 26 |
| Rauch et al. (14) | 2002 | H215O PET | 9 | No | 11 |
| Mataix-Cols et al. (15) | 2004 | 1.5-T fMRI | 33* | Yes (n = 12) | 30 |
| Schienle et al. (16) | 2005 | 1.5-T fMRI | 10 | Yes (n = 5) | 13 |
| Nakao et al. (17) | 2005 | 1.5-T fMRI | 10 | No | 7 |
| Shin et al. (18) | 2006 | H215O PET | 12 | Free for 4 wk | 1 |
fMRI = functional magnetic resonance imaging; OCD = obsessive–compulsive disorder; PET = positron emission tomography.
↵* This study involved 16 patients with OCD and 17 individuals without OCD.