Table 3

Clusters of significant likelihood for activation based on activation likelihood estimation

Anatomic region*BACoordinatesVolume, mm3ALE value (×10−3)Studies reporting foci of activation within the ALE cluster
xyzMcGuire et al. (11)Rauch et al. (12)Breiter et al. (13)Rauch et al. (14)Mataix-Cols et al. (15)Schienle et al. (16)Nakao et al. (17)Shin et al. (18)
L middle frontal gyrus11−2038−1463211.21
R lateral globus pallidus20−14053612.04
R medial frontal gyrus64303849611.77
R inferior frontal gyrus474820−1043212.37
L middle frontal gyrus9−42144036011.70
L inferior frontal gyrus47−2420−163449.69
L superior temporal gyrus38−4424−1830412.36
R inferior frontal gyrus454422424812.01
R uncus34166−1824011.44
R thalamus4−2441689.98
R middle frontal gyrus113246−121529.18
L lateral globus pallidus−12401288.9
L hippocampus−24−8−261128.1
L precuneus7−12−6650888.79
R inferior frontal gyrus473222−10648.87
R middle frontal gyrus10364610408.78
R anterior cingulate3212442328.53
R anterior cingulate3212420169.03
L cingulate gyrus24−2064488.17
  • ALE = activation likelihood estimate; BA = Brodmann areas; L = left; R = right.

  • * Nomenclature of cerebral areas and corresponding Brodmann areas are based on Talairach space.

  • p < 0.01, corresponding ALE threshold value = 6 × 10−3.

  • Fewer than 2 studies showed activation within the ALE cluster.