Table 4

Results of between-group analysis for PTSD patients and healthy control participants, shown for hypothesized areas, in which there was a significant BOLD response for the contrast of No-Go minus Go stimuli, with controlling for inhibitory error*

Area of interestHemisphereMNI coordinates, mmVoxelsz scorep value
xyz
Frontal cortex
 Inferior frontal/VLPFCR5432−8913.270.001
R4054−10703.140.001
L−5234−1282.810.002
 mPFC/dorsal ACCL−121432142.840.002
Precentral/inferior frontalR62−636112.770.003
Temporal cortexL−408−26923.38< 0.001
R68−28−14913.210.001
Parietal cortexL−54−4842782.920.002
R50−4038102.750.003
Cerebellum0−54−8683.45< 0.001
CuneusR4−8422223.050.001
PutamenL−30−206883.49< 0.001
PostcentralL−62−1822573.070.001
ParahippocampusL−28−42−6133.070.001
  • ACC = anterior cingulate cortex; BOLD = blood oxygen level dependent; L = left; MNI = Montréal Neurological Institute; mPFC = medial prefrontal cortex; PTSD= posttraumatic stress disorder; R = right; VLPFC = ventrolateral prefrontal cortex.

  • * Using total commission error as a covariate, significant differences in behaviour were found only between the healthy control group and the PTSD group.

  • Significance set at p < 0.005.