Table 2

Results of SVM classification of patients with MDD and controls using different brain morphometric features

	Morphometric feature, %

Brain region	Sensitivity	Specificity	Accuracy	p value
Left hemisphere
Cortical thickness	69	75	72	0.001
Volume	59	63	61	0.06
Pial area	69	69	69	0.003
Area	69	56	63	0.025
Curvature	44	56	50	0.53
Sulcal depth	56	63	59	0.08
Jacobian	63	56	59	0.07
Combined LH parameters	63	56	59	0.07
Right hemisphere
Cortical thickness	78	78	78	0.001
Volume	69	75	72	0.001
Pial area	66	66	66	0.008
Area	69	66	67	0.003
Curvature	63	59	61	0.05
Sulcal depth	59	59	59	0.08
Jacobian	69	66	67	0.004
Combined RH parameters	75	69	72	0.001
Combined LH and RH
Cortical thickness	66	72	69	0.002
Volume	63	69	66	0.005
Pial area	69	69	69	0.001
Area	66	53	59	0.10
curvature	47	50	48	0.63
Sulcal depth	56	59	58	0.12
Jacobian	63	72	67	0.002
Combined LH and RH parameters	69	69	69	0.002

LH = left hemisphere; MDD = major depressive disorder; RH = right hemisphere; SVM = support vector machine.