Table 5

Regions displaying high discrimination weights between patients with MDD and controls for volume measures

	Talairach coordinates

Brain region	x	y	z	W
MDD > control
Left hemisphere
Middle temporal gyrus	−54	−7	−28	5.65
Precentral gyrus	−63	−14	19	4.88
Superior frontal gyrus	−12	8	63	7.03
Supramarginal gyrus	−56	−49	33	5.83
Lateral occipital gyrus	−16	−94	18	6.59
Rostral anterior cingulate gyrus	−6	40	−3	8.41
Precuneus	−7	−65	23	4.92
Right hemisphere
Temporal pole	38	16	−33	8.07
Isthmus cingulate gyrus	7	−50	11	8.73
Rostral anterior cingulate gyrus	7	31	10	8.43
Superior frontal gyrus	14	15	60	6.26
Precentral lobule	54	−2	42	5.29
Insular lobe	37	−4	7	6.67
Rostral middle frontal gyrus	40	36	27	9.58
Control > MDD
Left hemisphere
Caudal middle frontal gyrus	−31	49	2	−6.77
Pars opercularis	−54	15	15	−5.41
Superior temporal sulcus	−49	−22	−8	−4.16
Superior temporal gyrus	−50	1	−14	−6.21
Postcentral gyrus	−44	−29	62	−6.75
Superior parietal lobular	−23	−60	58	−5.49
Pericalcarine	−16	−95	−2	−6.17
Medial orbitofrontal gyrus	−9	17	−17	−11.39
Fusiform gyrus	−27	−49	−15	−4.68
Right hemisphere
Middle temporal gyrus	62	−45	−5	−7.45
Superior temporal gyrus	62	−7	−2	−5.51
Supramarginal gyrus	57	−24	32	−8.03
Paracentral lobule	14	−42	74	−8.85
Precuneus	6	−59	49	−6.73
Lingual gyrus	16	−77	−11	−5.58
Entorhinal cortex	26	−7	−32	−5.78
Frontal pole	11	64	−6	−4.69