Hippocampal volumes in women with borderline personality disorder and healthy controls
| Region | Adjusted mean volumes, mm3 (SEM) | Group difference, % | ANCOVA* | ||
|---|---|---|---|---|---|
| BPD | Control | F1,35 | p value | ||
| DG-CA4 | |||||
| Left | 490 (11) | 536 (10) | 8.6 | 9.025 | 0.005 |
| Right | 511 (12) | 557 (12) | 8.3 | 7.193 | 0.011 |
| CA2–3 | |||||
| Left | 880 (22) | 966 (20) | 8.9 | 8.150 | 0.007 |
| Right | 921 (24) | 1021 (23) | 9.8 | 8.891 | 0.005 |
| CA1 | |||||
| Left | 290 (8) | 314 (7) | 7.6 | 5.002 | 0.032 |
| Right | 297 (9) | 325 (8) | 8.6 | 5.248 | 0.028 |
| Fimbria | |||||
| Left | 67 (3) | 65 (3) | −3.1 | 0.350 | 0.56 |
| Right | 64 (4) | 72 (4) | 11.1 | 1.455 | 0.24 |
| Subiculum | |||||
| Left | 575 (12) | 600 (11) | 4.2 | 2.155 | 0.15 |
| Right | 566 (16) | 585 (15) | 3.2 | 0.816 | 0.37 |
| Presubiculum | |||||
| Left | 446 (11) | 456 (10) | 2.2 | 0.443 | 0.51 |
| Right | 421 (11) | 446 (10) | 5.6 | 2.705 | 0.11 |
| Sum subfields | |||||
| Left | 3126 (58) | 3339 (54) | 6.4 | 7.021 | 0.012 |
| Right | 3160 (69) | 3403 (64) | 7.1 | 6.515 | 0.015 |
ANCOVA = analysis of covariance; BPD = borderline personality disorder; CA = cornu ammonis; DG = dentate gyrus; SEM = standard error of the mean.
↵* Age and subcortical grey matter volume were included as covariates.