Table 4

Regions displaying high discrimination weights between patients with MDD and controls for surface area measures

	Talairach coordinates

Brain region	x	y	z	W
MDD > control
Left hemisphere
Superior frontal gyrus	−10	3	67	9.61
Medial orbitofrontal gyrus	−10	40	−12	4.44
Cuneus	−5	−83	31	5.72
Parahippocampal gyrus	−22	−22	−25	5.38
Precuneus	−5	−59	16	5.23
Lateral occipital gyrus	−29	−93	10	5.93
Supramarginal gyrus	−55	−46	38	5.13
Precentral lobule	−58	4	26	5.85
Right hemisphere
Superior parietal lobule	46	−66	32	5.57
Lateral occipital gyrus	30	−87	12	5.28
Insular lobe	35	0	9	6.75
Rostral middle frontal gyrus	39	46	19	5.12
Inferior temporal gyrus	54	−38	−22	7.23
Postcentral lobule	51	−17	53	4.28
Caudal middle frontal gyrus	35	12	53	5.24
Superior frontal gyrus	16	12	60	6.02
Parahippocampal gyrus	21	−32	−12	5.34
Precuneus	10	−55	27	3.96
Control > MDD
Left hemisphere
Pars opercularis	−53	15	14	−6.11
Rostral middle frontal gyrus	−35	49	9	−5.62
Middle temporal gyrus	−60	−26	−13	−5.37
Superior parietal lobular	−26	−58	60	−7.40
Postcentral gyrus	−43	−28	62	−6.55
Lateral occipital gyrus	−15	−97	−11	−5.05
Pericalcarine	−14	−99	−2	−5.30
Medial orbitofrontal gyrus	−6	15	−15	−6.25
Rostral anterior cingulate gyrus	−6	31	16	−4.12
Right hemisphere
Superior temporal gyrus	59	0	−7	−7.12
Superior parietal lobule	16	−40	73	−5.11
Precentral gyrus	39	−10	61	−5.01
Supramarginal gyrus	56	−16	35	−4.73
Lateral occipital gyrus	25	−91	−10	−6.11
Middle temporal gyrus	56	−47	−7	−5.12
Inferior temporal gyrus	43	−3	−37	−6.68
Superior frontal gyrus	8	−4	41	−8.10
Entorhinal cortex	20	−9	−32	−5.66