Table 3

Regions of cortical thinning in rs1938526 risk allele carriers at p < 0.01, false discovery rate–corrected

Hemisphere; regionBAStereotaxic coordinates (MNI space)*t value at peak vertex
xyz
Right hemisphere
 Medial frontal gyrus/rectal gyrus11/10/25/32434−16−3.8
 Lingual gyrus/fusiform gyrus/culmen19/1825−67−5−3.63
 Parahippocampal gyrus/fusiform gyrus36/2039−29−26−3.49
 Inferior parietal lobule/postcentral gyrus40/3/535−3954−3.48
 Inferior parietal lobule/postcentral gyrus40/265−2528−3.3
 Lingual gyrus/inferior occipital gyrus18/173−92−7−3.28
 Superior and middle frontal gyri113452−13−3.25
 Cingulate gyrus/posterior cingulate/precuneus31/73−6427−3.25
 Inferior and medial frontal gyri/rectal gyrus/orbital gyrus11/47/252027−23−3.21
 Supramarginal gyrus4058−5433−3.18
 Medial frontal gyrus/precentral gyrus638−658−3.13
 Precuneus7/315−5844−3.08
 Middle frontal gyrus635059−3.02
 Inferior parietal lobule4045−5249−2.97
 Precuneus/superior occipital gyrus1936−8138−2.94
 Middle and superior frontal gyri10/112258−6−2.93
 Precuneus19/727−7429−2.93
 Medial frontal gyrus327851−2.78
 Middle and inferior occipital gyri1834−88−7−2.78
 Superior frontal gyrus6211765−2.76
 Middle temporal gyrus3753−650−2.76
Left hemisphere
 Superior and middle frontal gyri/precentral gyrus6/8/9−21854−4.09
 Inferior parietal lobule40−46−4246−4.07
 Precuneus31/7−4−6828−4.07
 Fusiform gyrus/parahippocampal gyrus36/37/20−41−37−23−3.92
 Inferior and medial frontal gyri/orbital gyrus47/11/25−2021−21−3.69
 Middle and inferior temporal gyri20/21/37−59−41−17−3.21
 Precentral gyrus6/43/4/44−58−111−3.20
 Middle and inferior occipital gyri/fusiform gyrus18/19−45−79−14−3.16
 Cingulate gyrus/precuneus31/7−8−4742−2.97
 Middle temporal gyrus37−55−64−3−2.74
 Middle frontal gyrus10−4255−7−2.68
 Middle temporal gyrus21−61−30−6−3.26
 Lingual gyrus/parahippocampal gyrus/culmen30/19−17−43−5−2.85
 Lingual gyrus18−2−81−4−2.89

  • BA = Brodmann area; MNI = Montreal Neurological Institute.

  • ↵* MNI coordinates refer to the maxima.