Crude and adjusted odds ratio of prevalent depression according to the highest decile and the doubling of the serum concentration of endostatin
| Group; factor | Crude OR (95% CI) | Adjusted OR (95% CI)* |
|---|---|---|
| Depressed at assessment, n = 63 | ||
| Highest decile of endostatin | 4.79 (1.56–14.75) | 1.78 (1.03–3.06) |
| Doubling of endostatin | 2.10 (1.46–3.01) | 1.93 (1.31–2.84) |
| Depressed in the past or at assessment, n = 165 | ||
| Highest decile of endostatin† | 2.89 (1.42–5.89) | 2.59 (1.57–4.28) |
| Doubling of endostatin | 1.62 (1.22–2.13) | 1.52 (1.11–2.07) |
| Depressed in the past but not at assessment, n = 102 | ||
| Highest decile of endostatin | 1.91 (0.79–4.64) | — |
| Doubling of endostatin | 1.29 (0.90–1.87) | — |
CI = confidence interval; OR = odds ratio.
↵* Analyses adjusted for smoking, history of coronary heart disease and stroke, high triglycerides plasma homocysteine and use of antidepressants. Age was not entered in the models because it did not confound the association between serum endostatin and depression status.
↵† Reference group: lowest decile of serum endostatin.