Table 4

Results of the multiple regression analysis between psychophysiological interactions (emotional > neutral pseudonames) and the Social Interaction Anxiety Scale in patients with social phobia*

MNI coordinates
Anatomic regionBACluster sizexyzr valuep value
Left amygdala seed
 SFG, SFG (orbital),10, 11386−34646−0.840.011
 MFG, Medial frontal gyrus (orbital)
Right amygdala seed
 SFG (medial), SFG,6, 8, 32325123260−0.740.023
 SMA, MCG
  • BA = Brodmann area; MCG = middle cingulate gyrus; MFG = middle frontal gyrus; MNI = Montreal Neurological Institute; SFG = superior frontal gyrus; SMA = supplementary motor area.

  • * p < 0.005, uncorrected (corrected at p < 0.05 on the cluster level using the AlphaSim procedure, which resulted in an empirically determined cluster-extent threshold of k = 260 voxels).