Demographic, lifestyle and clinical characteristics of men with and without depression at the time of collection of their blood samples
| Group; no. (%)* | ||||
|---|---|---|---|---|
| Characteristic | No depression, n = 1046 | Depression, n = 63 | Statistics | p value |
| Age, mean ± SD yr | 75.1 ± 4.1 | 75.7 ± 4.0 | t1107 = 1.17 | 0.24 |
| Education, completed high school | 498 (47.6) | 28 (44.4) | χ21 = 0.24 | 0.63 |
| Smoking history | χ22 = 8.41 | 0.015 | ||
| Never | 327 (31.3) | 10 (15.9) | ||
| Past | 659 (63.0) | 46 (73.0) | ||
| Current | 60 (5.7) | 7 (11.1) | ||
| Body mass index | χ23 = 10.66 | 0.014 | ||
| Normal | 369 (35.3) | 17 (28.8) | ||
| Underweight | 7 (0.7) | 2 (3.4) | ||
| Overweight | 516 (49.4) | 25 (42.4) | ||
| Obese | 152 (14.6) | 15 (25.4) | ||
| Antidepressant use | 75 (7.2) | 14 (22.2) | χ21 = 18.24 | < 0.001 |
| Diabetes | 148 (14.1) | 11 (17.5) | χ21 = 0.53 | 0.47 |
| Hypertension | 491 (46.9) | 31 (49.2) | χ21 = 0.12 | 0.73 |
| Coronary heart disease | 346 (33.1) | 33 (52.4) | χ21 = 9.84 | 0.002 |
| Stroke | 123 (11.8) | 23 (36.5) | χ21 = 31.84 | < 0.001 |
| HDL cholesterol ≤ 1 mmol/L | 186 (17.8) | 15 (23.8) | χ21 = 1.45 | 0.23 |
| LDL cholesterol ≥ 3 mmol/L | 444 (42.4) | 24 (38.1) | χ21 = 0.46 | 0.50 |
| Triglycerides ≥ 1.7 mmol/L | 263 (25.1) | 27 (42.9) | χ21 = 9.65 | 0.002 |
| High sensitivity CRP ≥ 3 nmol/L | 338 (32.3) | 26 (41.3) | χ21 = 2.16 | 0.14 |
| Homocysteine ≥ 15 μmol/L | 274 (26.2) | 27 (42.9) | χ21 = 8.34 | 0.004 |
| Endostatin: highest decile (≥ 8.6 nmol/L)† | 94 (9.0) | 17 (27.0) | χ29 = 24.55 | 0.004 |