Table 2

Gene-based tests of miR-185 target genes

Gene*ChromosomeMinimal p valueNo. of SNPspSIDAK valuepZ FIX value
ADAMTS1950.005107> 0.99> 0.99
ANXA2150.00850> 0.99> 0.99
APBA19< 0.001109> 0.99> 0.99
APP21< 0.0011530.53> 0.99
ARID1A10.01313> 0.99> 0.99
ATAT16< 0.00116< 0.001> 0.99
CDC4210.01122> 0.99> 0.99
FAM134C17< 0.00117> 0.99> 0.99
FMO21< 0.00150> 0.99> 0.99
FOXN314< 0.001281> 0.99> 0.99
KCNN310.016135> 0.99> 0.99
LPHN1190.00512> 0.99> 0.99
NFASC1< 0.001151> 0.99> 0.99
NTRK315< 0.0011870.220.002
PAK615< 0.00136> 0.990.13
PBX11< 0.001237> 0.99> 0.99
PRX190.00215> 0.99> 0.99
PTPRE10< 0.001132> 0.99> 0.99
RHOA30.01417> 0.99> 0.99
RIC8B120.01243> 0.99> 0.99
SERF215< 0.00116> 0.990.91
SH3PXD2A10< 0.0011300.0080.06
SLC30A320.00613> 0.99> 0.99
SLC37A211< 0.00141> 0.99> 0.99
SNX1911< 0.001530.18> 0.99
SYNGAP160.00817> 0.99> 0.99
SYNM15< 0.00157> 0.990.25
TCF1215< 0.001114> 0.99> 0.99
TJP115< 0.001113> 0.99> 0.99
VEZF1170.02015> 0.99> 0.99
ZNF385A12< 0.00170.30> 0.99
  • SNP = single nucleotide polymorphism.

  • * Thirty-one miR-185 target genes that showed nominal association with schizophrenia according to at least 1 of the 2 applied methods (SIDAK, Z FIX).

  • Single marker.

  • Corrected for multiple testing.