Cohort demographic and clinical descriptives of tissue sample donors within the Depression Collection
| Group; mean (range)* | ||||
|---|---|---|---|---|
| Descriptive | Control | MD (total) | MDP | MDNP |
| No. of patient donors | 12 | 24 | 11 | 12 |
| Age at death, yr | 46.8 (24–62) | 42.2 (24–63) | 39.6 (28–63) | 42.8 (24–56) |
| Illness duration, yr | — | 11.7 (0.1–31) | 11 (3–21) | 12.3 (0.1–31) |
| Age at illness onset, yr | — | 29.7 (13–45) | 28.6 (13–39) | 30.5 (14–45) |
| Sex, male:female | 8:4 | 13:11 | 5:6 | 7:5 |
| PMI, h | 25.3 (9–65) | 29.6 (13–65) | 33.1 (19–52) | 23.6 (13–38) |
| Refrigeration, h† | 7.42 (3–18) | 7.96 (1–31) | 7.18 (1–14) | 8 (2–31) |
| pH | 6.64 (6.31–6.57) | 6.6 (6.3–6.9) | 6.6 (6.3–6.74) | 6.7 (6.52–6.9) |
| Hemisphere, right:left | 6:6 | 15:9 | 8:3 | 7:5 |
| Antipsychotics‡ | 0 | 12 | 9 | 3 |
| Fluphenazine equivalents | — | 2 242 (100–6 500) | 2 533 (100–6 500) | 1 367 (100–3 000) |
↵MD = major depression; MDNP = major depression without psychosis; MDP = major depression with psychosis; PMI = postmortem interval.
↵* Unless otherwise indicated.
↵† Values refer to the mean interval between patient death and refrigeration of the body at the medical examiner’s office.
‡ Number of patients with a prescription for antipsychotics at the time of death.