Table 2

Functional MRI results across all participants during the choice phase*

Phase; regionSideMNI coordinatesZ scoreCluster sizeCluster p value
xyz
A. Linear increase in risk-related activity during the choice phase (extent threshold p < 0.05 FWE)
 Ventral striatumL−166−8> 85382< 0.001
R1610−8> 8
 ThalamusR8−22−4> 8
 Anterior insulaL−2816−66.68
R3222−105.45
 Dorsomedial prefrontal cortexL−634306.935254< 0.001
 Anterior cingulate cortexR1030266.39
 Middle occipital cortexL−34−76366.93429< 0.001
R44−76186.16624< 0.001
 CerebellumR8−62226.35233< 0.001
L−8−58−204.84
 Posterior cingulate cortexL−6−32306.25472< 0.001
R10−36305.44
 PrecuneusL−12−68326.201334< 0.001
R16−64485.88
 Middle temporal cortexL−54−50125.95624< 0.001
 Middle frontal cortexL−2228505.6161< 0.001
 Inferior frontal cortexL−468185.56151< 0.001
 Lateral orbitofrontal cortexL−424805.3256< 0.001
 Precentral gyrusR48−8445.31137< 0.001
B. Positive linear association between risk-related increase in neural activity during the choice phase and individual neuroticism scores
 Ventral striatumL−128−104.13600.044
R204−103.53490.06
C. Positive linear association between risk-related increase in neural activity during the choice phase and individual risk taking ratio
 Superior temporal sulcusR52−32224.112150.035
D. Negative linear association between risk-related increase in neural activity during the choice phase and individual risk taking ratio
 Rostral dorsal premotor cortexR264605.062320.026
 Inferior frontal gyrusR4816344.632440.021
 MidbrainL−6−6−164.592720.013
 InsulaL−3226−44.40630.041
 Superior parietal lobuleR26−74544.36503< 0.001
 Dorsomedial prefrontal cortexR842304.245110.001
R426484.14
  • FWE = familiy-wise error; L = left; MNI = Montreal Neurological Institute; R = right.

  • * Regional peaks (cluster p FWE < 0.05; clusters ≥ 40 voxels; extend threshold p ≤ 0.001, uncorrected, unless otherwise stated). Z statistics and cluster size in voxels.