Phase; region | Side | MNI coordinates | Z score | Cluster size | p value | ||
---|---|---|---|---|---|---|---|
x | y | z | |||||
A. Negative outcomes: large missed monetary reward following low-risk choice > small missed monetary rewards following high-risk choice | |||||||
Ventral striatum | L | −12 | 8 | −6 | 5.39 | 389 | 0.005 |
Caudate nucleus | L | −8 | 8 | 6 | 4.73 | ||
Ventral striatum | R | 10 | 10 | 10 | 4.48 | 188 | 0.09 |
B. Positive outcomes: high monetary reward following high-risk choice > low monetary reward following low-risk choice (extend threshold p < 0.05, FWE-corrected) | |||||||
Middle temporal gyrus | R | 58 | −44 | 6 | 6.22 | 272 | < 0.001 |
Anterior cingulate cortex | L | −10 | 36 | 14 | 6.18 | 544 | < 0.001 |
R | 12 | 42 | 16 | 6.12 | |||
Hippocampus | R | 16 | −24 | −10 | 5.89 | 141 | < 0.001 |
Thalamus | L | −12 | −2 | 4 | 5.89 | 231 | < 0.001 |
R | 4 | −4 | 4 | 4.92 | |||
Posterior cerebellum | R | 26 | −76 | 28 | 5.57 | < 0.001 | |
Inferior frontal gyrus | R | 50 | 34 | 20 | 5.47 | 46 | < 0.001 |
Anterior insula | R | 28 | 20 | −12 | 5.32 | 118 | < 0.001 |
L | −30 | 16 | −14 | 5.37 | 46 | < 0.001 | |
Fusiform gyrus | L | −40 | −58 | −20 | 5.18 | 49 | < 0.001 |
FWE = familiy-wise error; L = left; MNI = Montreal Neurological Institute; R = right.
* Regional peaks (cluster pFWE < 0.05; clusters ≥ 40 voxels; extend threshold p ≤ 0.001 uncorrected unless otherwise stated). Z statistics and cluster size in voxels.