Table 2

Risk of bias in individual studies included in the meta-analysis

StudySequence generationAllocation concealmentBlinding of participants, personnel and outcome assessorsIncomplete outcome dataSelective outcome reportingOther sources of bias
Alvarez et al.24+++?++
Henigsberg et al.27++????
Baldwin et al.25+++++?
Katona et al.30+++???
Mahableshwarkar et al.29+++?+?
Jain et al.28++?+++
Boulenger et al.26+++?++
Mahableshwarkar et al.32+++?+?
Jacobsen et al.31+++?+?
Mahableshwarkar et al.33+++?+?
NCT0125578734+++?+?
Dragheim et al.35+++?+?
  • + = clear; ? = unclear, based on Cochrane systematic review values.