Clusters of fractional anisotropy reductions in patients with bipolar disorder relative to healthy controls
| Maximum | Cluster | ||||
|---|---|---|---|---|---|
| Region | MNI coordinates x, y, z | SDM Z value | p value | Number of voxels | Breakdown (number of voxels) |
| Genu of corpus callosum | −10, 28, 16 | −2.209 | ~0 | 388 | Corpus callosum (321) Left striatum (21) Left anterior thalamic projections (20) Left inferior fronto-occipital fasciculus (15) Left cingulum (11) |
| Body of corpus callosum | −18, −32, 32 | −2.470 | ~0 | 180 | Corpus callosum (125) Left cingulum (43) Left superior longitudinal fasciculus (12) |
| Body of corpus callosum | 16, −6, 36 | −1.303 | <0.001 | 127 | Corpus callosum (112) Right anterior thalamic projections (15) |
MNI = Montreal Neurological Institute; SDM = signed differential mapping.