Patient data on randomization, active contacts and stimulating parameters at the beginning of the trial and the medications prescribed at trial entry
| Patient | Trial arm | Active electrodes | Stimulation parameters | Pharmacological treatment |
|---|---|---|---|---|
| Patient 1 | OFF-ON | L 0(−) 2(+) | A = 4.5 V | Duloxetine (120 mg/d) |
| R 4(−) 6(+) | D = 210 μs | Quetiapine (1000 mg/d) | ||
| F = 135 Hz | Lorazepam (2 mg/d) | |||
| Patient 2 | ON-OFF | L 0(−) 3(+) | A = 5 V | Venlafaxine (300 mg/d) |
| R 4(−) 7(+) | D = 180 μs | Mirtazapine (60 mg/d) | ||
| F = 135 Hz | Lithium (400 mg/d) | |||
| Diazepam (30 mg/d) | ||||
| Quetiapine (200 mg/d) | ||||
| Patient 3 | ON-OFF | L 0(−) 1(+) | A = 5 V | Duloxetine (90mg/d) |
| R 5(−) 6(+) | D = 180 μs | Mirtazapine (30mg/d) | ||
| F = 135 Hz | Olanzapine (5mg/d) | |||
| Diazepam (50mg/d) | ||||
| Alprazolam (6mg/d) | ||||
| Zolpidem (10mg/d) | ||||
| Levomepromazine (50 mg/d) | ||||
| Pregabaline (300mg/d) | ||||
| Patient 4 | ON-OFF | L 0(−) 1(+) | A = 4 V | Duloxetine (120 mg/d) |
| R 4(−) 5(+) | D = 180 μs | Mirtazapine (60 mg/d) | ||
| F = 135 Hz | Valproate (1500 mg/d) | |||
| Trazodone (200 mg/d) | ||||
| Lorazepam (5mg/d) | ||||
| Midazolam (7.5 mg/d) | ||||
| Patient 5 | OFF-ON | L 0(−) 2(+) | A = 3.5 V | Imipramine (100 mg/d) |
| R 4(−) 6(+) | D = 120 μs | Medazepam (10 mg/d) | ||
| F = 135 Hz |
A = amplitude; D = pulse width; F = frequency; L = left electrode; OFF–ON = 3 mo of sham stimulation followed by 3 mo of active stimulation; ON–OFF = 3 mo of active stimulations followed by 3 mo of sham stimulation; R = right electrode.