Table 2

[¹⁸F]fallypride binding potential values for the PFC ROI and the midbrain

	Cravers (n = 9); mean ± SEM				Noncravers (n = 3); mean ± SEM

ROI	Neutral cues	Cocaine cues	%ΔBP_ND	p value^*	Neutral cues	Cocaine cues	%ΔBP_ND	p value^*
mOFC	0.538 ± 0.077	0.430 ± 0.067	−20.1	0.010^†	0.663 ± 0.173	0.810 ± 0.231	22.1	0.038
latOFC	0.626 ± 0.080	0.593 ± 0.075	−5.8	0.18	0.696 ± 0.134	0.776 ± 0.163	11.4	0.07
mPFC	0.462 ± 0.061	0.414 ± 0.052	−10.4	0.14	0.656 ± 0.191	0.663 ± 0.151	1.1	0.90
DLPFC	0.456 ± 0.062	0.411 ± 0.055	−9.9	0.11	0.593 ± 0.137	0.646 ± 0.143	8.9	0.27
ACC	0.562 ± 0.057	0.500 ± 0.045	−11.0	0.040	0.716 ± 0.168	0.800 ± 0.182	11.7	0.07
VTA	1.700 ± 0.150	1.581 ± 0.133	−7.0	0.12	1.686 ± 0.504	1.90 ± 0.431	12.6	0.11
SN/VTA	2.128 ± 0.178	1.993 ± 0.118	−6.3	0.23	2.136 ± 0.294	2.330 ± 0.086	9.1	0.45

ACC = anterior cingulate cortex; BP_ND = binding potential; DLPFC = dorsolateral prefrontal cortex; lat = lateral; m = medial; OFC = orbitofrontal cortex; PFC = prefrontal cortex; ROI = region of interest; SEM = standard error of the mean; SN = substantia nigra; VTA = ventral tegmental area.
↵* All p values derived from post hoc comparisons, except those for the VTA and SN/VTA, which were derived from paired-samples t tests.
↵† p < 0.05 following Bonferroni correction.