Demographic and clinical characteristics of the study sample
| Group, mean ± SD* | |||
|---|---|---|---|
| Characteristic | Control, n = 29 | MDD, n = 43 | p value |
| Age, yr | 34.5 ± 10.7 | 37.1 ± 10.9 | 0.32 |
| Education, yr | 14.9 ± 2.6 | 10.4 ± 1.5 | 0.009 |
| Sex, male:female | 11:18 | 17:26 | — |
| Duration of illness, yr | — | 7.2 ± 7.1 | — |
| No. of episodes | — | 3.1 ± 1.9 | — |
| BDI score | 1.5 ± 2.4 | 29.0 ± 9.3 | < 0.001 |
| HAMD score | 0.9 ± 1.7 | 20.9 ± 5.1 | < 0.001 |
| TIV, mL | 1417.5 ± 125.9 | 1352.2 ± 114.6 | 0.026 |
BDI = Beck Depression Inventory; HAMD = Hamilton Rating Scale for Depression; MDD = major depressive disorder; SD = standard deviation; TIV = total intracranial volume.
↵* Unless otherwise indicated.