Anhedonia and anxiety measures in healthy controls and patients with schizophrenia, by sex
| Controls; mean ± SD* | Patients; mean ± SD* | Group; statistic,†p value | |||||
|---|---|---|---|---|---|---|---|
| Measure | Men | Women | Men | Women | Diagnosis | Sex | Diagnosis × sex |
| Chapman Scales | n = 17 | n = 18 | n = 27 | n = 26 | λ2,83 = 3.44, p = 0.037 | λ2,83 = 4.54, p = 0.013 | λ2,83 = 0.59, p = 0.56 |
| Physical anhedonia | 16.0 ± 7.6 | 9.4 ± 5.6 | 17.9 ± 7.6 | 14.7 ± 8.4 | F = 4.84, p = 0.031 | F = 8.97, p = 0.004 | F = 1.06, p = 0.31 |
| Social anhedonia | 10.5 ± 6.2 | 7.3 ± 5.4 | 13.4 ± 6.6 | 11.0 ± 6.6 | F = 5.88, p = 0.017 | F = 4.16, p = 0.045 | F = 0.06, p = 0.80 |
| LSAS | n = 17 | n = 17 | n = 26 | n = 25 | λ4,78 = 6.80, p < 0.001 | λ4,78 = 0.79, p = 0.54 | λ4,78 = 0.57, p = 0.69 |
| Social fear | 3.5 ± 4.3 | 5.9 ± 6.2 | 12.3 ± 8.2 | 12.0 ± 7.6 | F = 23.00, p < 0.001 | F = 0.46, p = 0.50 | F = 0.76, p = 0.39 |
| Performance fear | 3.9 ± 4.2 | 6.2 ± 5.0 | 12.7 ± 7.7 | 12.2 ± 8.3 | F = 23.76, p < 0.001 | F = 0.34, p = 0.56 | F = 0.78, p = 0.38 |
| Social avoidance | 3.4 ± 3.8 | 5.0 ± 6.3 | 13.1 ± 9.6 | 10.4 ± 7.2 | F = 21.31, p < 0.001 | F = 0.10, p = 0.75 | F = 1.74, p = 0.19 |
| Performance avoidance | 3.4 ± 4.7 | 4.5 ± 5.3 | 12.5 ± 8.1 | 10.5 ± 7.5 | F = 24.68, p < 0.001 | F = 0.09, p = 0.77 | F = 1.06, p = 0.31 |
| LSAS total (ANCOVA) | 14.2 ± 13.5 | 21.6 ± 21.7 | 50.6 ± 31.2 | 45.2 ± 27.7 | F = 28.00, p < 0.001 | F = 0.03, p = 0.86 | F = 1.29, p = 0.26 |
| Social Function Scale total | 835 ± 49 | 868 ± 24 | 755 ± 79 | 802 ± 58 | F = 31.96, p < 0.001 | F = 9.91, p = 0.002 | F = 0.30, p = 0.58 |